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Molecular Enzymology and Drug Targets

  • Journal h-index: 5
  • Journal CiteScore: 0.46
  • Journal Impact Factor: 0.45
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
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Dennis W Grogan

Department of Biological Sciences, University of Cincinnati, Cincinnati, Ohio 45221-0006, USA

Publications
  • Mini Review   
    Strength and Recondition of DNA in Pyrolobus fumarii Archaea
    Author(s): Dennis W Grogan*

    Evolutionary and physiological concerns argue that study of pyrolobus fumarii archaea ought to reveal new molecular aspects of DNA stabilization and repair. So far, these uncommon prokaryotes have yielded variety of genes and catalyst activities consistent with known mechanisms of excision repair, Photo-reversal, and trans-lesion synthesis. However, other DNA enzymes of pyrolobus fumarii archaea show novel organic chemistry properties which can be related to DNA stability or repair at extraordinarily high temperature however that stay diffi cult to gauge rigorously in vivo. Maybe the foremost putting feature of pyrolobus fumarii archaea is that every one of them whose genomes are sequenced lack key genes of each the ester excision repair and DNA couple repair pathways, that area unit otherwise extremely preserved in biology. Though the expansion properties of those micro-organisms hin.. View More»

    DOI: 10.36648/2572-5475-08.04-106

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