Department of Rheumatology, Bolan Medical College Quetta, Pakistan
Research Article
Inflammatory Arthritis and Younger Age of Lupus Onset are Associated with the Development of Neuropsychiatric Lupus
Author(s): Dr. Asadullah Khan* and Dr. Muhammad Haroon
Neuropsychiatric Systemic lupus erythematous (NPSLE) refers to the various psychiatric and neurologic manifestations that develop secondary to involvement of the nervous system in patients with SLE [1, 2]. These clinical features occur either due to a diffuse neurological insult (e.g. encephalopathy, coma, depression, and psychosis) or a localized neurologic insult (e.g. stroke or seizure etc) [3]. Because of the varied diagnostic criteria associated with these manifestations, the American College of Rheumatology (ACR) has formulated case definitions, reporting standards, and diagnostic testing recommendations for the 19 neuropsychiatric SLE syndromes [4]. The prevalence of neurologic and psychiatric manifestations using the ACR case definitions follows the following order from most to least: cognitive dysfunction, headache, mood disorder, cerebrovascular disease, seizures, polyneurop.. View More»
Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 