Department of Paediatric Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Research Article
Comparison of Risperidone and Aripiprazole for the Treatment of Irritability Associated with Autism Spectrum Disorder
Author(s): Gopen Kumar Kundu*, Sadia Sultana, Choudhury Rehnuma Tabassum and Ishrat Zahan Nigar
Background: Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with high heterogeneity. While the symptoms of ASD can manifest before 2 years of age, they usually become more apparent between 2 and 3 years of age. Patients with ASD are all unique in their presentation; however, the disorder is characterized by core symptoms that include impairments in social interaction and communication, as well as the presence of restricted and repetitive behaviors. Risperidone and aripiprazole are most commonly used drugs for the treatment of irritability and aggressive behaviour in children with autism spectrum disorder.
Objective: To compare the efficacy and safety of risperidone and aripiprazole for the management of core symptoms of children with ASD.
Materials and methods: This prospective interventiona.. View More»