Translational Biomedicine

  • ISSN: 2172-0479
  • Journal h-index: 16
  • Journal CiteScore: 5.91
  • Journal Impact Factor: 3.66
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
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Hendry Joseph

Department of Disease Mechanisms, Somalia

  • Mini Review   
    Unveiling Disease Mechanisms: A Journey into Understanding the Inner Workings of Human Ailments
    Author(s): Hendry Joseph*

    Disease mechanisms form the foundation of medical research, serving as the cornerstone for understanding the complexities of human ailments. This article explores the intricate processes underlying disease development and progression, encompassing genetic variations, cellular dysfunction, immune responses, and environmental influences. Genetic discoveries, facilitated by genomic sequencing technologies and genome-wide association studies, have unveiled disease-causing genes and genetic mutations. At the cellular level, dysfunctions in signaling pathways, protein misfolding, and mitochondrial abnormalities contribute to disease manifestation. Immunological disorders, often stemming from deregulated immune responses, result in autoimmune conditions and chronic inflammation. Furthermore, environmental triggers and epigenetic modifications have emerged as influential factors in disease me.. View More»

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