Department of Pharmaceutics, BN University Udaipur Rajasthan, India
Review Article
A Review Article on Formulation and Evaluation of Amoxycillin and Potassium Clavulanate Dispersible Tablets
Author(s): Imam Razi* and Mishra Amul
The present work is aimed to develop a stable formulation of preferred combination of two Antibiotics Amoxycillin and Potassium Clavulanate by using various disintegrants.They are Prepared by direct compression method using different disintegrant i.e croscarmellose Sodium, cross povidone, Maize Starch and sodium starch Glycolate. Aspartame as sweetener and strawberry flavours were used to increase palability. The powder blends were subject to various characterstics test such as bulk density, tapped Density, Haushners ratio and combressibility index. These tablets were evaluated for hardness, friability, disintegration time and wetting time and in vitro drug release. Amoxycillin and Potassium clavulanate dispersible tablets were found to be of good quality fulfilling all the requirements for dispersible tablets.The result indicated that concentration of cross povidone, cross carmellose.. View More»
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