Department of Laboratory Medicine and Pathology, Division of Transfusion Medicine, Mayo Clinic Rochester, Minnesota, United States
Research Article
Cold Whole Blood Transfusion in Civilian Trauma Patients Requiring Emergent Resuscitation: A Retrospective Cohort Study
Author(s): Marianna Martini Fischmann, Sandra C. Bryant, Martin D. Zielinski and James R. Stubbs*
Background: The use of cold Whole Blood (WB) is rapidly resurging as one of the treatment modalities of choice for the initial resuscitation of civilian trauma patients across the United States. The purpose of our study was to evaluate the effectiveness and safety of cold Whole Blood (WB) as compared to Blood Component Therapy (BCT) in resuscitation of civilian trauma patients.
Methods: This was a retrospective cohort study of trauma patients who received at least one unit of WB transfusion during emergent resuscitation between November 2015 and October 2019 at a level I trauma center. Primary outcome was mortality up to 30 days after trauma. Secondary outcomes included overall blood product utilization and incidence of transfusion reactions. Outcomes were compared between patients who received WB and a cohort receiving BCT who did not recei.. View More»
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