Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA, USA
Review Article
Recent Progress on Hepatitis C Vaccine Development: A Systematic Review.
Author(s): Princess Halm, Sumana Kondle* and Derek Sun
Chronic hepatitis C is one of the most common causes of liver disease and cancer
world-wide. 20% of cases of chronic hepatitis are at high risk to develop cirrhosis and
amongst them there is a 4%-5% annual incidence rate of hepatocellular carcinoma.
Around the world, HCV infection is one of the leading causes of permanent
liver damage, and related deaths, especially due to end-stage liver disease and
hepatocellular carcinoma. Emerging data suggest that viral cure reduces, but
does not eliminate the risk for hepatocellular carcinoma (HCC) development. The
question that this paper seeks to find the answer to is, are there any In vitro or in
vivo trials, currently being executed to discover a hepatitis C vaccine for those at
risk, or already afflicted with, hepatitis C. If so, what is the perceived plausibility
that an effective one is soon in the making? To.. View More»
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