Department of Cellular and Molecular Biology, University of Cincinnati, Saudi Arabia
Review
A Knowledge from a Molecular Docking Study on the Mycobacterium Tb Arabinosyltransferase C Enzyme as a Possible Therapeutic Target
Author(s): Sachita Varma*
One of the main obstacles to treating and curing tuberculosis is the fact that Mycobacterium tuberculosis is multi-drug resistant. Numerous anti-tubercular medications lack effectiveness as a result of M. tab’s established drug resistance mechanism. Therefore, research has been done globally to create potent anti-TB medications to enhance the treatment of these strains. Due to a lack of a structure-based approach, traditional drug development methods have been shown to be ineffective in the development of broad-spectrum drugs. In this context, numerous researches have been carried out and a number of drug target sites that affect drug-resistant Mtb strains have been found. The goal of this study was to determine how the two current medicines and five modified compounds produced from ethambutol interacted with the protein Arabinosyltransferase C. With Auto Dock, a molecular docki.. View More»
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