Department of Enzymology, University of Gujarat, India
Mini Review
Unraveling the Architectural Complexity of Enzymes: Implications for Function, Evolution, and Therapeutics
Author(s): Sashi Sharma*
Enzymes, the remarkable catalysts orchestrating the myriad chemical
reactions within living organisms, exhibit an astounding architectural
complexity that underlies their diverse functions and evolutionary
history. Understanding the intricacies of enzyme structure has farreaching
implications, spanning from fundamental biochemical insights
to practical applications in therapeutics and biotechnology. In this
article, we embark on a journey to unravel the mysteries of enzyme
architecture, exploring how their three-dimensional arrangements
dictate catalytic efficiency, substrate specificity, and intricate regulatory
mechanisms. Through a comprehensive review of cutting-edge
research, we shed light on the evolutionary forces that have shaped
these molecular machineries and led to the remarkable diversity of
enzymes across different species and ecosystem.. View More»
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