Molecular Enzymology and Drug Targets

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Smrity Yadav

Department of Biotechnology, SR Group of Institutions, Lucknow, India

  • Mini Review   
    Exploring the Role of Glycolysis in Cancer Metabolism: Implications for Rigid Therapies
    Author(s): Smrity Yadav*

    Cancer metabolism has emerged as a crucial determinant in tumor development and progression, with dysregulated metabolic pathways supporting the energy demands of rapidly proliferating cancer cells. Among these metabolic alterations, glycolysis, a process that converts glucose into pyruvate, has gained significant attention due to its unique impact on cancer cell survival and proliferation. In this study, we investigate the pivotal role of glycolysis in cancer metabolism and explore its potential implications for targeted therapies. Through in vitro analyses, we demonstrate that cancer cells exhibit enhanced glycolytic activity, a hallmark feature of the Warburg effect, compared to their normal counterparts. Gene expression analysis reveals upregulation of key glycolytic enzymes, substantiating the importance of glycolysis in cancer cells' energy me.. View More»

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