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International Journal of Drug Development and Research

  • ISSN: 0975-9344
  • Journal h-index: 49
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Soni Gaurav

Department of Pharmacology, Lords University, Alwar, Rajasthan, India

Publications
  • Research Article   
    In-Vivo Anti-Inflammatory Potential of Malvastrum Tricuspidatum
    Author(s): Soni Gaurav*

    Anti-inflammatory activity of plant Malvastrum tricuspidatum was evaluated by in-vivo (carrageenan induced paw edema in rats) method. To evaluate anti-inflammatory activity; rats were divided into four groups each having six rats. Group I served as carrageenan control group and received carrageenan only. Group II received aqueous plant extract (200 mg/kg), group III received aqueous plant extract (400 mg/kg) and Group IV received Indomethacin (10 mg/kg, p.o). Paw volume was measured using digital plethysmometer at 1, 2, 3 and 4 hr. Percentage inhibition of paw edema of each group were determined.  The oral administration of 200 mg/kg, 400 mg/kg of the plant extract significantly (p<0.05) inhibited inflammatory response induced by carrageenan in rats in a dose related manner. The most prominent inhibition was recorded for 400 mg/kg (45.45%) at 4 hr of study wh.. View More»

    DOI: 10.36648/0975-9344.22.14.1003

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