Ouattara Souleymane, A Lamien, A Traore, F A H A Ido, A S Ouedraogo, A R ouiminga and O M Lompo
Scientific Tracks Abstracts: Arch Clin Microbiol
Systemic aspergillosis is a disease increased in immunocompromise terrain as HIV, chronic immunosuppressant/steroid use. We report the case of a 39-year-old female patient who had an antecedent of chronic lymphocytic leukemia treated. The patient developped focal neurologic deficits, mental status changes, headache. CT scan of the head shows a large left frontal hypodense, nonenhancing lesion with mass effect. Intra-operative cytopathology show perivascular lymphocyts. On microscopic study, we diagnosed true hyphae with septations Grocott + , vasculitis leading to necrosis. On some areas, their was an abondant inflammation composed with small lymphocyts and plasmocyts. An immunostain with antibodies anti- CD20, anti-CD3, anti-CD5, anti-CD23, anti-IgD and anti- Kappa and Lamda was realize in hospital of Paris. Their was no argument for secondary localisation of CLL. Cerebral aspergillosis is rarely seen. His diagnosis is multidisciplinar. The pathologist need to exchange with clinicians and radiologists.
Ouattara Souleymane currently working at Ouagadougou, Burkina Faso and he completed his studies Université de Ouagadougou, Burkina Faso Science • Ouagadouga, Kadiogo, Burkina Faso. He published many research works in many journals. His research interested is Digital Pathology.