Archives of Clinical Microbiology

  • ISSN: 1989-8436
  • Journal h-index: 19
  • Journal CiteScore: 6.52
  • Journal Impact Factor: 0.72
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
20+ Million Readerbase
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • The Global Impact Factor (GIF)
  • Open Archive Initiative
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Proquest Summons
  • Publons
  • MIAR
  • University Grants Commission
  • Geneva Foundation for Medical Education and Research
  • Google Scholar
  • Scimago Journal Ranking
  • Secret Search Engine Labs
  • ResearchGate
Share This Page

Control and degradation of patulin in apples by Pichia caribbica and the possible mechanisms involved

10th Edition of International Conference on Advanced Microbiology & Education
June 14-16, 2018 London, UK

Hongyin Zhang, Qiya Yang and Lina Zhao

Jiangsu University, P R China

Posters & Accepted Abstracts: Arch Clin Microbiol


The efficacy of Pichia caribbica in controlling postharvest blue mold and natural decay development of apples and degrading the patulin were investigated. The decay incidence of the blue mold of apples treated by P. caribbica was significantly reduced compared with the control samples and the higher the concentration of P. caribbica, the better the efficacy of the biocontrol. P. caribbica significantly controlled the natural decay development of apples following storage at 20°C for 35 days or 4°C for 45 days followed by 20°C for 15 days. Germination of spores and growth of Penicillium expansum were markedly inhibited by P. caribbica in in vitro test. Rapid colonization of apple wounds by the yeast was observed in fruit stored at 20°C or 4°C. After incubation with P. caribbica at 20°C for 15 days, patulin production by P. expansum in apples was significantly reduced compared with the control. In vitro test indicated that P. caribbica can degrade patulin directly. Our results suggested that the mechanism of degradation of patulin by P. caribbica was not absorption; the presence of patulin can induce P. caribbica to produce associated intracellular and extracellular enzymes, both of which have the ability to degrade patulin. The result provides a new possible method that used the enzymes produced by yeast to detoxify patulin in food and feed.