Flyer

Archives of Clinical Microbiology

  • ISSN: 1989-8436
  • Journal h-index: 19
  • Journal CiteScore: 6.52
  • Journal Impact Factor: 0.72
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
20+ Million Readerbase
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • The Global Impact Factor (GIF)
  • Open Archive Initiative
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Proquest Summons
  • Publons
  • MIAR
  • University Grants Commission
  • Geneva Foundation for Medical Education and Research
  • Google Scholar
  • Scimago Journal Ranking
  • Secret Search Engine Labs
  • ResearchGate
Share This Page

Drug resistance and large fragment polymorphism of Mycobacterium tuberculosis isolated from Qinghai

Joint Event on 3rd International Confrence on Digital Pathology & 7th Global Summit on Microbiology Research
August 13-14, 2018 Madrid, Spain

Zhaofen Wang, Xiuli Shen, Mingxia Jiang and Bin Li

Qinghai University, China

Posters & Accepted Abstracts: Arch Clin Microbiol

Abstract:

Qinghai is located in the northeast of the Qinghai-Tibet Plateau. 236 strains of Mycobacterium tuberculosis isolated in Qinghai were identified and drug resistance was tested by using the proportional method; the relationship between TB drug resistance and the demographic characteristics were analyzed. The drug resistance rate of the 236 strains of Mycobacterium tuberculosis was 55.93%. Four first-line drug resistance rates from high to low were 43.22% for isoniazid, 38.14% for streptomycin, 37.29% for rifampin and 28.81% for ethambutol. MDR-TB and XDR-TB were 30.93% and 1.27%, respectively. The single resistance of first-line drugs was 12.71%, resistant to two or more than two of first-line drugs were 43.22%. Drug-resistance TB associated with regions and ages, and did not associate with gender and ethnicity. The drug-resistance TB in Qinghai area is higher than the national level. A total of 237 clinical isolates of M. tuberculosis in this area were genotyped by PCR for the deletions of RD105 ï¼?RD181ï¼?RD150ï¼?RD142 and RD239ï¼?Among 237 isolates, 220 were identified as “Beijing family” and 17 were “non-Beijing family” by RD105 deletion, accounting for 92.83% and 7.17%, respectively. The 220 “Beijing family” were further identified by RD181 deletion as the modern “Beijing family” (198 isolates, 90.00%) and atypical “Beijing family” (22 isolates, 10.00%).

Biography :

Zhaofen Wang has completed her Masters from Qinghai University, China. She is a Professor and a Director at the Qinghai University and has over 70 publications.

E-mail: [email protected]