Annals of Clinical and Laboratory Research

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Proportion of, and factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan

4th Edition of International Conference on Clinical Chemistry & Molecular Diagnostics
April 15-16, 2019 | Paris, France

Mohammad Naeem, Ahmed Nasir and Jamshid Jalal

FMIC, Afghanistan

Posters & Accepted Abstracts: Ann Clin Lab Res


Background: The thyroid gland, located just below the vocal cord on each side of and anterior to the trachea, is one of the main endocrine glands. Its normal weight is 15 to 20 grams in adults. The thyroid secretes two most important hormones, thyroxine and triiodothyronine, usually called T4 and T3, respectively. These hormones greatly increase the metabolic rate of the body. In addition to T3 and T4, the thyroid gland secrets calcitonin as well which is a significant hormone for calcium metabolism.

Objective: The aim of this study is to estimate the proportion of, and to identify factors associated with thyroid dysfunction among individuals coming to a tertiary care facility in Kabul, Afghanistan.

Material & Methods: An analytical cross-sectional study design was conducted from Jul’ to Sep’ 2018. Blood samples were obtained, serum TSH levels were measured, and the patients were divided into three diagnostic categories according to their serum TSH concentrations: hypothyroidism; hyperthyroidism and normal thyroid

Results: A total of 127 individuals were part of the sample for the final analysis. Majority study participants (77%) were females. A large number of the participants (92%) did not have family history of thyroid dysfunction and majority of the female participants, (85%) were not pregnant in the last two years. Furthermore, 98% participants were non-smokers.

Conclusion: The findings of the current study showed a high prevalence of thyroid dysfunctions in individuals coming to FMIC for thyroid functions tests. The findings also indicated that aging and smoking are the factors associated with thyroid dysfunctions. Further studies are needed to find out the prevalence of and factors associated with thyroid dysfunctions.

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