Flyer

Journal of Neurology and Neuroscience

  • ISSN: 2171-6625
  • Journal h-index: 15
  • Journal CiteScore: 2.13
  • Journal Impact Factor: 1.45
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Indexed In
  • Open J Gate
  • Genamics JournalSeek
  • The Global Impact Factor (GIF)
  • China National Knowledge Infrastructure (CNKI)
  • Directory of Research Journal Indexing (DRJI)
  • OCLC- WorldCat
  • Proquest Summons
  • Scientific Journal Impact Factor (SJIF)
  • Euro Pub
  • Google Scholar
  • Secret Search Engine Labs
Share This Page

Abstract

ISAAC syndrome

Sumeet Swapan Roy*, Raghav Kapoor, Rahul Saini and Nikita Goel

ISSAC Syndrome is a form of peripheral nerve hyperexcitability caused by continuous muscle fiber activity. The patient usually presents with the complaints of twitching and stiffness. Symptoms such as myokymia and muscle spasm, may persist during sleep. The patients are reported to be CASPR2 antibody positive which is ought to be the pathogenic antibody in ISSAC Syndrome. The patients are commonly treated with immunomodulatory therapies which includes steroids, plasma exchange therapy and rituximab for nonresponsive cases. Treatment also includes symptomatic management which has no effect on disease progression.

Published Date: 2022-04-30; Received Date: 2022-04-08