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Major Considerations on the Clinical, Epidemiological, Histopathological and Therapeutic Aspects of Ameloblastomas: A Systematic Review

Luciana Fortes Tosto Dias, Rogerio Luiz de Araujo Vian, Pedro Miguel Nunes, Henrique Esteves Magalhaes, Claudiane da Silva Maia do Carmo, Eduardo Costa Figueiredo Passos and Luciano Rodrigues Neves

The Ameloblastoma is a benign epithelial tumor which presents local infiltrativo behavior, being that the jaw is the most affected region. Has a silent evolution, being difficult to diagnose at first. In accordance with their clinical characteristics, the ameloblastoma corresponds to 1% of the tumors and cysts present in the jaws. In relation to existing clinical types, are found three: unicystic, multicystic and peripheral. The objective of this work is to carry out a literature review of published articles from 2003 to 2019 in journals indexed in databases, on the main aspects, clinical, epidemiological and therapeutic ameloblastomas histopathological that the dental surgeon should be able to recognize. Following literary search criteria with the use of the MeSH Terms that were cited in the item on "Search strategies", a total of 35 clinical studies that were submitted to the eligibility analysis were checked, and after that, 20 studies were selected, following the rules of systematic review-PRISMA. Ameloblastoma is a tissue tumor of the enamel organ, benign and of ectodermal origin and corresponds to 1% of the tumors and cysts present in the region of the jaws. The region of greatest incidence of this type of tumor is in the mandible, usually in the posterior region (molar region) and ascending branch. The highest incidence during the third and fourth decades of life. There is no prevalence of sex. It is divided into three clinical types: multicystic, unicystic and peripheral, being the prevalence of multicystic, representing 85% of the cases.