Department of Medicine, Sommaiya medical college and Hospital, Mumbai, India
Case Report
Case based discussion: A rare case of empty sella syndrome in an adult female
Author(s): Pradeep Kumar Vyas*, Vaishnavi Gurumurthy, Vidyadhara Lakkappan, Lipeeka parulekar, Rakesh singh and Arunav uchil
Empty sella syndrome (ESS) is pathophysiologically characterized
by either anatomic abnormalities in the diaphragma sellae
(primary ESS), damage to the pituitary by irradiation/surgery, or
autoimmunity leading to the availability of “empty” space in the sella
(secondary ESS). The most prevalent hormone deficiency is growth
hormone (GH), affecting 35% to 61% of adult patients with ESS. The
most common symptom is headache which is deep, dull, and central.
Sometimes headache is very severe, with giddiness and vomiting. In
primary ESS, the sella tends to be symmetrically ballooned without
evidence of bony lesions. The suprasellar subarachnoid space
herniates through an incomplete sellar diaphragm. Cisternography,
high resolution CT scanning, or MRI is used for diagnosis. The signs
and symptoms depend upon the size, secretion, and.. View More»