International Journal of Drug Development and Research

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Dr. Mamata Mishra

Senior Research Scientist, Jai Research Foundation, Research & Development Section, JRF Global, Valvada, Gujarat-396105, India

  • Research Article   
    The trans-differentiation of Keratinocyte: Requisite for skin wound healing and cosmetic surgery
    Author(s): Dr. Mamata Mishra*

    Objective: Skin wound healing involves the interaction of epidermal and dermal cells, growth factors, and cytokines. Keratinocyte is the most dominant cell type in the epidermis and plays multiple roles for skin repair function. Cultured human primary keratinocytes are required for the treatment of burns, cutaneous wounds diabetic foot ulcers, and cosmetic therapy Methods: Human primary keratinocytes from different age groups were isolated, characterized and efficacy was analyzed. Primary human keratinocytes were purchased from commercially available sources and their trans-differentiation properties were studied. Results: Serum-free media with high calcium was used to isolate keratinocytes from different donors with varied age groups. The number of keratinocytes isolated from the total popul.. Read More»

    DOI: 10.36648-0975-9344-15.2-997

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