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Journal of Neurology and Neuroscience

  • ISSN: 2171-6625
  • Journal h-index: 18
  • Journal CiteScore: 4.35
  • Journal Impact Factor: 3.75
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
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Marcus Lowe

Transplantation Laboratory, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, United Kingdom

Publications
  • Review Article   
    A review of the risk factors, pathophysiology, diagnosis and treatment of narcolepsy
    Author(s): Steven Jervis*, Anthony Payton, Arpana Verma, Marcus Lowe, Rachel Thomasson and Kay Poulton

    Narcolepsy is hypothesized to be an autoimmune disease targeting the hypocretin/orexin producing neurons within the hypothalamus and is categorised into subsets based on the symptoms presented. Epidemiological studies have proposed that there is an additional requirement for an environmental trigger combined with potential genetic predisposition to trigger the onset of this spectrum of disorders. Despite epidemiological evidence which suggests the condition arises due to a breach of immunological tolerance, the absence of a defined autoantigen remains an element of debate in the aetiology of the disorder. Currently there are no definitive diagnostically useful genetic variants observed in narcolepsy suffers which could be exploited at disease onset to support its diagnosis or clinical management The most impactful genetic risk factor.. View More»

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