Department of Orthopedics and Traumatology Surgery, University of Granada, Alzira, Valencia, Spain
Mini Review
Increased lung exposure to inhaled drugs through pharmaceutical means
Author(s): Stephen Borghardt*
The pulmonary administration approach has been extensively
utilized for the treatment of both local lung diseases like asthma,
chronic obstructive pulmonary disease, and respiratory infections as
well as systemic disorders like diabetes. The majority of medications
taken by inhalation pass quickly through the lungs and have brief
therapeutic effects. By reducing the number of times a patient is
given a medication, prolonged pulmonary exposure from inhaled
medications may not only improve therapeutic outcomes but also
clinical benefits for patients. This article provides a comprehensive
analysis of the physical and chemical strategies for increasing the
pulmonary exposure of inhaled medications. It begins by providing
an overview of the numerous physiological and pathophysiological
challenges that must be overcome in order to create inhal.. View More»
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