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Health Science Journal

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Evaluation of Lung Functionality after Discharge in Hospitalized Patients with Severe COVID-19 Pneumonia

XX Congresso Regionale FADOI CAMPANIA: Non ci siamo mai fermati
Italy 2021

Langella V, Asti A, Di Palma G, Maresca G, Pomponi D, Russo S and Russo V

Department of Internal Medicine, â�?�? S. Maria di Loreto Nuovo â�?, Covid Center Hospital, ASLNA1, Napoli (IT), Italy
Department of Internal Medicine, â�?�? S. Paolo â�? Hospital, ASLNA1, Napoli (IT), Italy
Department of Medical Translational Sciences, University of Campania, Monaldi Hospital, Napoli (IT), Italy

Posters & Accepted Abstracts: Health Sci J

Abstract:

COVID19 causes SIRS with extensive lung damage that requires follow-up to evaluate possible sequelae. Based on British Thoracic Society suggests, considering elevated number of patients and a reasonable use of medical resources, we evaluated patients discharged for severe pneumonia with spirometry at 5 and 12 weeks and DLCO at 12 weeks only in patients with spirometric abnormality. Functional test were correlated with CTscan. From November'20 to March'21,86 patients (37F, age Ì�?5Ì�?3Ì�?.Ì�?7Ì�?) were enrolled. 61 refused follow-up or didn’t perform examinations, 234 with history of smoking, emphysema, asthma/COPD were not considered. Pulmonary microembolism was detected in 54.To avoid extreme data we used a stepwise regression analysis, including demographics data, pre-existing conditions, severity and ICU admission. At 5 weeks, an alteration was found in 18 (20.9%). At 12 weeks, an alteration was found in 13 (15.1%), with a prevalence of 4.6% of a restrictive pattern and 10.4% of an obstructive pattern. The radiological alterations was resolved in almost all patients (90.7%). A mild alteration DLCO was found in 3 patients, all with restrictive spirometry pattern. In 4(3F) there was persistence of microembolism. Patients undergoing pulmonary rehabilitation program showed a greater and rapid improvement. In our observation, a lower prevalence of impaired respiratory function (15.1%) was found compared to other studies. Our data, like others, support the hypothesis that early functional evaluation could overestimate COVID damage. Pulmonary rehabilitation must be considered as a valid strategy. References 1. British Thoracic Society (2020) British Thoracic Society Guidance on Respiratory Follow Up of Patients with a Clinico-Radiological Diagnosis of COVID-19 Pneumonia. 2. George PM, Barrat SL, Confliffe R, Desai SR, Devaraj A, et al. (2020) Respiratory follow up of patients with COVID-19 pneumonia. Thorax.

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