Health Science Journal

  • ISSN: 1108-7366
  • Journal h-index: 61
  • Journal CiteScore: 17.30
  • Journal Impact Factor: 18.23
  • Average acceptance to publication time (5-7 days)
  • Average article processing time (30-45 days) Less than 5 volumes 30 days
    8 - 9 volumes 40 days
    10 and more volumes 45 days
Awards Nomination 20+ Million Readerbase
Indexed In
  • Genamics JournalSeek
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • CINAHL Complete
  • Scimago
  • Electronic Journals Library
  • Directory of Research Journal Indexing (DRJI)
  • EMCare
  • OCLC- WorldCat
  • University Grants Commission
  • Geneva Foundation for Medical Education and Research
  • Euro Pub
  • Google Scholar
  • Secret Search Engine Labs
Share This Page

Lymphoproliferative Disease in Retroperitoneal Fibrosis: a Case Report

XX Congresso Regionale FADOI CAMPANIA: Non ci siamo mai fermati
Italy 2021

Serpico R, Casaburi C, Ambrosino A and Ranucci RAN

U.O.C. Medicina Interna, Ospedaleâ�? S.M. delle Grazieâ�?, Pozzuoli (NA), Italy

Posters & Accepted Abstracts: Health Sci J


Background: Idiopathic retroperitoneal fibrosis, named Ormond disease, is a rare, connective tissue disease. In the idiopathic form, in over 70% of the cases, the growth of the fibrous tissue involves mediastinic site, orbital tissue, biliary tract, thyroid. In more one third of the cases retroperitoneal fibrosis is due to several causes: infections, trauma, radiation, drugs, neoplasms. The idiopathic form is due to IgG4 related disease, a sistemic fibro-inflammatory disease characterized by infiltration of IgG4 positive plasma cells in the affected tissues, with or without elevated plasma levels of IgG4. Case history: We report a clinical case of a patient 70 years old, affected by dilatative cardiomyopathy with sistolic disfunction, diabetes, hypertension. He is hospitalized for dyspnea. In the chest X ray left pleural effusion, so for that reason he did a CT scan that showed us mediastrinic and retroperitoneal fibrosis and multiple district lymphadenomegaly. At blood chemistry tests mild anemia, mild leukopenia with lymphocytosis, increase of tumor markers. At immunofixation monoclonal component IgG lambda in gamma region. The flow cytometry with monoclonal antibodies showed a lymphoproliferative disease. Conclusion: This is a rare case of secondary fibrosis due to lymphoproliferative disease although monoclonal component IgG. Differential diagnosis is very hard.