Agus Trianto, Ocky Karna Radjasa and Agus Sabdono
Diponegoro University, Indonesia
Scientific Tracks Abstracts: Arch Med
The marine sponges are the most productive source of bioactive compounds with potential application in human health such as anticancer, antibacterial, anti-inflammatory and antioxidant. However, some research proved that the associated microorganisms, such as fungi are the original producers of the bioactive compounds or the precursor. This research aims to obtain the sponges associated fungi that produce bioactive compounds. The sponge specimens were collected from six stations in Ternate Island, Moluccas, Indonesia by the diving method. The fungi were isolated by tapping methods. The isolates were cultured on malt extract agar media in the room temperature until fully covered by the petri dish before they are refreshed and transferred into a small tube. The isolates were tested against Escherichia coli, Klebsiella pneumonia, Bacillus subtilis, MRSA, and Acinetobacter baumannii. The most active isolates were identified using molecular method. Isolation of the 54 sponges provided a total of 158 isolates.
1. Agus Trianto, Ocky Karna Radjasa, Agus Sabdono, Sakti Imam Muchlissin, Rachmat Afriyanto, Sulistiowati, Septhy Kusuma Radjasa, Phillip Crews and Erin Mccauley (2019) Exploration culturable bacterial symbionts of sponges from Ternate Islands, Indonesia. Biodiversitas Journal of Biological Diversity 20(3):776-782.
2. Erin McCauley, Ocky Karna Radjasa, Agus Trianto, Mitchell S Crews, Alexander Smith, Gavin C Smith, Paul Zerebinski, Agus Sabdono and Phillip Crews (2018) The UNDIP-UCSC campaign to culture chemically prolific gram-negative bacteria from Indonesian Jaspis sponges. The Free Internet Journal for Organic Chemistry IV 123-131.
3. Walter Balansa, Agus Trianto, Nicole J de Voogd and Junichi Tanaka (2017) new cytotoxic polyacetylenic alcohol from a sponge Callyspongia sp. Natural Product Communications. 12(12):1909-1911.
4. Agus Trianto, Ocky Karna Radjasa, Rudhi Pribadi, Sekar Widyaningsih, Khoeruddin Wittriansyah, Isei Yusidharta, Wiratno, and Ita Riniatsih (2017) Exploration of Marine Sponges-Associated Fungi Producing Antifungal Compounds. Asian Journal of Microbiology Biotechnology & Environmental Science 19(3):588- 593.
5. Agus Trianto, Nicole J de Voodg and Junichi Tanaka (2014) Two new compounds from an Indonesian sponge Dysidea sp. Journal of Asian natural products research 16(2):163-168.
Agus Trianto is a Researcher in the Department of Marine Science, Faculty of Fisheries and Marine Science, Diponegoro University. He obtained the BSc degree in Marine Science from Diponegoro University in 1993. He got the Master and Doctoral degree on Marine Natural Product from the University of Ryukyus in 2000 and 2011, respectively. Since, 2012 he got a position as secretary of Marine Science Study Program, then became the Head of Marine Science Study Program of Diponegoro University in 2017. Since, 2000 he conducted research mainly on natural product focusing on search of bioactive compounds from marine invertebrates such as sponge, gorgonian, tunicate and soft coral. From 2015, he has been working on sponges associate microorganisms to produce the bioactive compounds in a larger amount continuously. He published paper more than 50 papers both in international and national journals on natural product and related fields.