Dept. of Basic Sciences, College of Dentistry, Ibn Sina University of Medical and Pharmaceutical Sciences, Baghdad, Iraq
Research Article
The Role of Exosome and Protein Kinase cGMP-dependent 1 (PRKG1) in Detecting of Breast Cancer in patients with Breast Tumors.
Author(s): Nawfal K. Khiro* and Nadia N. Hasan
Background: Breast cancer is responsible for the death of millions of women worldwide every year. Several clinical, diagnostic and pathological techniques have been introduced to get early detection of the disease. One of these techniques was developed to detect extracellular vesicle exosomes and phosphoproteins as a product of cancer cells.
Objective: Investigating the role of exosome and (PRKG1) in detection breast cancer in patients with breast tumors.
Subjects and Methods: This case-control study was conducted on women. They were divided into 3 groups, group me of patients with malignant breast tumor, group II of patients with benign breast tumor, and group III which of matched healthy subjects as control. Ten milliliters of blood sample was obtained from patients submitted for surgery (mastectomy or lumpectomy.. View More»
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