Department of Chemical and Environmental Engineering, University of South Carolina, South Africa
Mini Review
By Preventing -Glucosidase and -Amylase Noncompetitively, Phenols from Sterculia Nobilis Smith Pericarp In-Products Postpone the Digestion of Carbohydrates
Author(s): Pooja Bhatiya*
The functional activity and phytochemical makeup of Sterculia Nobilis Smith pericarp, a byproduct of this tropical and subtropical fruit, have not received much attention. The LC-ESIMS/MS-MRM technique was employed in this study to analyse 16 phenolic compounds in the ethyl acetate fraction of the Sterculia Nobilis Smith pericarp extract on a qualitative and quantitative level. The main phenolic in the EAF were luteolin-7-O-glucoside, epicatechin gallate, and apigetrin. Models of inhibition of -glucosidase and -amylase were used to investigate the hypoglycemic action of EAF. With half-inhibitory concentration levels, EAF inhibited -glucosidase and -amylase activities in a reversible and non-competitive manner. The EAF's enzyme inhibition mechanism was investigated using spectroscopic techniques. The outcomes demonstrated that EAF changed the secondary structure and microenvironmen.. View More»
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